Since its inception in 1953, the Cancer Research Institute (CRI) has had a singular mission—to foster research that will yield an understanding of the immune system and its response to cancer, with the ultimate goal of developing immunological methods for the treatment, control, and prevention of the disease. To accomplish this, CRI funds and coordinates an international network of laboratory and clinical research scientists working within the fields of immunology and tumor immunology. Through integration of basic and clinical research initiatives, CRI is accelerating the discovery, testing, and optimization of next-generation cancer immunotherapies such as cancer vaccines and antibodies. The Cancer Research Institute identifies top scientific talent through the guidance of the CRI Scientific Advisory Council (SAC), an international roster of leaders in the field of immunology who support CRI’s efforts to foster creative, scientifically rigorous research. The SAC counts among its members three Nobel Laureates, 31 members of the National Academy of Sciences, and 24 members of the Academy of Cancer Immunology.